| Primary Identifier | MGI:99701 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 12531 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein kinase binding activity and protein tyrosine phosphatase activity. Acts upstream of or within female meiosis I; oocyte maturation; and positive regulation of protein kinase activity. Located in cytoplasm and nucleus. Is expressed in several structures, including 1-cell stage embryo; cerebral cortex ventricular layer; gonad; placenta; and primitive collecting duct. Orthologous to human CDC25B (cell division cycle 25B). PHENOTYPE: The resumption of meiosis during oocyte maturation is blocked in homozygous mutant female mice, resulting in female infertility. Male mice do not show an overt reproductive phenotype. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
