Primary Identifier | MGI:1332236 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 110911 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidate cytidylyltransferase activity. Involved in lipid droplet formation. Located in endoplasmic reticulum. Is expressed in several structures, including central nervous system; immune system; retina; skin; and testis. Orthologous to human CDS2 (CDP-diacylglycerol synthase 2). PHENOTYPE: Mice homozygous for disruptions in this gene display a lethal phenotype. Heterozygotes show a distorted lymphocyte distribution and enhanced sensorimotor gating. [provided by MGI curators] |