| Primary Identifier | MGI:2444678 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 228677 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable serine C-palmitoyltransferase activity. Predicted to be involved in ceramide biosynthetic process and sphingosine biosynthetic process. Predicted to act upstream of or within sphingoid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of serine palmitoyltransferase complex. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; respiratory system; and sensory organ. Orthologous to human SPTLC3 (serine palmitoyltransferase long chain base subunit 3). PHENOTYPE: Mice with loss of expression in hepatocytes display impaired hepatocytic gluconeogenesis and reduced fasting blood glucose levels when on a high-fat diet. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
