Primary Identifier | MGI:105372 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 20608 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable neuropeptide binding activity and somatostatin receptor activity. Predicted to be involved in several processes, including neuropeptide signaling pathway; positive regulation of arachidonate secretion; and regulation of signal transduction. Predicted to be active in neuron projection and plasma membrane. Is expressed in several structures, including genitourinary system; gut; nervous system; respiratory system; and sensory organ. Orthologous to human SSTR4 (somatostatin receptor 4). PHENOTYPE: Homozygote null mice have increased susceptibility to inflammation, delayed type hypersensitivity, hyperalgesia and airway hypersensitivity. [provided by MGI curators] |