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Protein Coding Gene : Acss1 acyl-CoA synthetase short-chain family member 1
Primary Identifier  MGI:1915988 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  68738
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables acetate-CoA ligase activity and propionate-CoA ligase activity. Acts upstream of or within acetyl-CoA biosynthetic process. Located in mitochondrial matrix. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human ACSS1 (acyl-CoA synthetase short chain family member 1).
PHENOTYPE: Mice with disruptions in this gene display abnormalities in acetate metabolism. Ability to maintain body temperature under fasting conditions is reduced. [provided by MGI curators]
  • synonyms:
  • Acas2,
  • acetyl-Coenzyme A synthetase 2 (AMP forming)-like,
  • acetyl-Coenzyme A synthetase 2,
  • Acss1,
  • RIKEN cDNA 1110032O15 gene,
  • MGI:2139052,
  • expressed sequence AI788978,
  • Acas2l,
  • AceCS2,
  • AI788978,
  • acyl-CoA synthetase short-chain family member 1,
  • 1110032O15Rik
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Features --> Cross References

Genome

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2 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

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Homology

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Interactions

4 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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