Primary Identifier | MGI:2385955 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 246700 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable lipopolysaccharide binding activity. Predicted to be involved in antifungal innate immune response; defense response to Gram-negative bacterium; and defense response to Gram-positive bacterium. Predicted to be located in extracellular region. Is expressed in metanephros and reproductive system. Used to study female reproductive system disease. Orthologous to human DEFB119 (defensin beta 119). PHENOTYPE: Mice homozygous for a null allele exhibit reduced female fertility due to reduced ability to attract sperm. [provided by MGI curators] |