Primary Identifier | MGI:1097696 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 19700 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transmembrane transporter binding activity. Acts upstream of or within negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel and regulation of skeletal muscle contraction by calcium ion signaling. Located in I band and T-tubule. Is expressed in alimentary system and urinary system. Orthologous to human REM1 (RRAD and GEM like GTPase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a moderate increase in L-type calcium channel current density in cardiac myocytes but show no overt cardiac phenotype at baseline. [provided by MGI curators] |