| Primary Identifier | MGI:96396 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 15901 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transcription regulator inhibitor activity. Involved in circadian rhythm; negative regulation of cold-induced thermogenesis; and regulation of gene expression. Acts upstream of or within several processes, including BMP signaling pathway; lung development; and negative regulation of macromolecule biosynthetic process. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human ID1 (inhibitor of DNA binding 1). PHENOTYPE: Homozygotes for knockout alleles of both Id1 and Id3 exhibit vascular malformations in the forebrain, lack of vascular branching and sprouting in the neuroectoderm, and impaired angiogenesis in transplanted and spontaneous tumors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
