| Primary Identifier | MGI:96052 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 15162 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including lipid binding activity; non-membrane spanning protein tyrosine kinase activity; and phosphotyrosine residue binding activity. Acts upstream of or within defense response to Gram-positive bacterium and phagocytosis. Predicted to be located in several cellular components, including caveola; cytoplasmic side of plasma membrane; and focal adhesion. Predicted to be active in plasma membrane. Predicted to colocalize with actin filament. Is expressed in several structures, including 2-cell stage embryo; bone; eye; limb; and nervous system. Orthologous to human HCK (HCK proto-oncogene, Src family tyrosine kinase). PHENOTYPE: Macrophages from mice homozygous for a targeted null mutation exhibit impaired phagocytosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
