| Primary Identifier | MGI:107688 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 16569 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables intraciliary transport particle B binding activity. Involved in anterograde dendritic transport of neurotransmitter receptor complex; cilium assembly; and vesicle-mediated transport. Located in centrosome; cilium; and dendrite. Part of kinesin II complex. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including gonad; gut; hemolymphoid system gland; nervous system; and nose. Used to study schizophrenia. Human ortholog(s) of this gene implicated in retinitis pigmentosa 89. Orthologous to human KIF3B (kinesin family member 3B). PHENOTYPE: Mice homozygoous for a targeted null mutation are growth retarded and display neural tube defects, incomplete embryo turning, randomized left-right assymetry, pericardial edema, and die during the midgestational period. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
