Primary Identifier | MGI:1923657 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 76407 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein-membrane adaptor activity. Involved in spermatid development. Acts upstream of or within protein-containing complex assembly; regulation of protein localization; and spermatogenesis. Located in sperm head-tail coupling apparatus. Human ortholog(s) of this gene implicated in spermatogenic failure 16. Orthologous to human SUN5 (Sad1 and UNC84 domain containing 5). PHENOTYPE: Homozygous knockout causes male sterility owing to sperm head to flagella connection anomalies. [provided by MGI curators] |