| Primary Identifier | MGI:1338036 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 18843 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable lipid binding activity. Involved in antibacterial humoral response; innate immune response; and negative regulation of single-species biofilm formation in or on host organism. Predicted to be located in extracellular region and microvillus. Predicted to be active in extracellular space. Is expressed in hemolymphoid system; nose; respiratory system; and turbinate bone. Used to study otitis media. Orthologous to human BPIFA1 (BPI fold containing family A member 1). PHENOTYPE: Mice homozygous for a knock-out or ENU-induced allele exhibit increased susceptiblity to Mycoplasma pneumoniae infection. Club cell-specific conditional or constitutive homozygous KO also increases susceptibility to Influenza A virus infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
