Primary Identifier | MGI:1913616 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 66366 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; positive regulation of intracellular protein transport; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment. Predicted to be part of retrograde transporter complex, Golgi to ER. Predicted to be active in COPII-coated ER to Golgi transport vesicle; Golgi membrane; and endoplasmic reticulum membrane. Is expressed in cerebellum; neocortex; and spleen. Orthologous to human ERGIC3 (ERGIC and golgi 3). PHENOTYPE: Knockout mice exhibit enlarged heart ventricles and decreased heart ventricular contractility. [provided by MGI curators] |