Primary Identifier | MGI:2151841 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 228852 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable enzyme inhibitor activity and myosin phosphatase regulator activity. Acts upstream of or within establishment of endothelial barrier. Predicted to be located in nuclear speck; perinuclear region of cytoplasm; and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; eye; heart; hemolymphoid system; and spinal cord. Orthologous to human PPP1R16B (protein phosphatase 1 regulatory subunit 16B). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and grossly normal with no detectable defects in thymopoiesis. [provided by MGI curators] |