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Protein Coding Gene : Chd6 chromodomain helicase DNA binding protein 6

Primary Identifier  MGI:1918639 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  71389
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and transcription coregulator binding activity. Predicted to be involved in cell redox homeostasis; chromatin remodeling; and positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin and nucleoplasm. Predicted to be active in nucleus. Is expressed in cerebral cortex intermediate zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human CHD6 (chromodomain helicase DNA binding protein 6).
PHENOTYPE: Homozygous null mice display impaired coordination that is not due to muscle weakness or bradykinesia. [provided by MGI curators]
  • synonyms:
  • Chd6,
  • 5430439G14Rik,
  • RIKEN cDNA 5430439G14 gene,
  • chromodomain helicase DNA binding protein 6,
  • 6330406J24Rik,
  • RIKEN cDNA 6330406J24 gene,
  • MGI:1921259

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