Primary Identifier | MGI:1918639 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 71389 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and transcription coregulator binding activity. Predicted to be involved in cell redox homeostasis; chromatin remodeling; and positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin and nucleoplasm. Predicted to be active in nucleus. Is expressed in cerebral cortex intermediate zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human CHD6 (chromodomain helicase DNA binding protein 6). PHENOTYPE: Homozygous null mice display impaired coordination that is not due to muscle weakness or bradykinesia. [provided by MGI curators] |