| Primary Identifier | MGI:109634 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 21749 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables telomeric repeat DNA binding activity. Acts upstream of or within meiotic telomere clustering. Located in chromosome, telomeric region and nucleus. Part of nuclear telomere cap complex. Is expressed in several structures, including 2-cell stage conceptus; 4-8 cell stage conceptus; blastocyst-stage conceptus; genitourinary system; and telencephalon. Orthologous to human TERF1 (telomeric repeat binding factor 1). PHENOTYPE: Mice homozygous for disruptions in this gene display embryonic lethality and die sometime before E7.5 [provided by MGI curators] |