Primary Identifier | MGI:1933159 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 81018 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and plasma membrane. Is expressed in central nervous system; early conceptus; and genitourinary system. Orthologous to human RNF114 (ring finger protein 114). PHENOTYPE: Mice homozygous for a null allele exhibit female infertility with reduced oocyte number and maternally influences failure of zygotic cell division. [provided by MGI curators] |