| Primary Identifier | MGI:88593 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 13081 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 25-hydroxycholecalciferol-24-hydroxylase activity. Acts upstream of or within vitamin D metabolic process. Located in mitochondrion. Is expressed in axial skeleton; cranium; ear; genitourinary system; and nervous system. Human ortholog(s) of this gene implicated in colorectal adenoma; gastrointestinal system cancer (multiple); hypercalcemia; lung cancer (multiple); and ulcerative colitis. Orthologous to human CYP24A1 (cytochrome P450 family 24 subfamily A member 1). PHENOTYPE: Mice homozygous for disruption of this gene suffer a 50% mortality rate between birth and weaning. abnormalities are seen in the development of membranous bones. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
