| Primary Identifier | MGI:2676869 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 387136 |
| Mgi Type | miRNA gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within cellular response to leukemia inhibitory factor; post-transcriptional regulation of gene expression; and regulation of calcineurin-NFAT signaling cascade. Part of RISC complex. Is expressed in several structures, including brain; early conceptus; heart; oocyte; and somite. Orthologous to human MIR1-1 (microRNA 1-1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit partial lethality before weaning and subtle cardiac defects, including intermittent atrial arrhythmias, mild ventricular dilation, and conduction abnormalities. Lethality is strain-dependent. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
