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Protein Coding Gene : Ppdpf pancreatic progenitor cell differentiation and proliferation factor
Primary Identifier  MGI:1913746 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  66496
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within TORC1 signaling and liver development. Is expressed in several structures, including esophagus; forelimb bud; and male reproductive gland or organ. Used to study metabolic dysfunction-associated steatotic liver disease. Orthologous to human PPDPF (pancreatic progenitor cell differentiation and proliferation factor).
PHENOTYPE: Liver-specific knock-out mice develop fatty liver disease. [provided by MGI curators]
  • synonyms:
  • 0610012G23Rik,
  • RIKEN cDNA 2700038C09 gene,
  • MGI:1919783,
  • RIKEN cDNA 2610317A05 gene,
  • RIKEN cDNA 3110053G12 gene,
  • 3110053G12Rik,
  • RIKEN cDNA 0610012G23 gene,
  • Ppdpf,
  • MGI:1913313,
  • pancreatic progenitor cell differentiation and proliferation factor,
  • MGI:1920465,
  • 2610317A05Rik,
  • 2700038C09Rik
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