Primary Identifier | MGI:88270 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 12350 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables nickel cation binding activity. Acts upstream of or within response to bacterium. Located in cytosol. Is expressed in several structures, including ear; genitourinary system; heart; limb; and musculoskeletal system. Orthologous to human CA3 (carbonic anhydrase 3). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile and exhibit a normal life span and a normal response to hyperoxic challenge. Mutant muscles display shorter half-relaxation times for both single and tetanic twitches but show normal fatigability. [provided by MGI curators] |