| Primary Identifier | MGI:1923203 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 75953 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of gene expression, epigenetic and retinal rod cell development. Located in cytoplasm and nucleus. Part of PRC1 complex. Is expressed in central nervous system; dorsal root ganglion; liver; metanephros; and neural retina. Human ortholog(s) of this gene implicated in macular degeneration. Orthologous to human SAMD7 (sterile alpha motif domain containing 7). PHENOTYPE: Homozygous knockout reduces the sensitivity of the retinal rods to low-to-moderate flash luminescence. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
