| Primary Identifier | MGI:2150386 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 114893 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in positive regulation of protein neddylation; protein neddylation; and regulation of protein ubiquitination. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of ubiquitin ligase complex. Is expressed in several structures, including central nervous system; genitourinary system; liver; lung; and spleen. Orthologous to human DCUN1D1 (defective in cullin neddylation 1 domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele are runted with spleen and lymphoid hypoplasia and decreased mouse embryonic fibroblast proliferation. Males are infertile and exhibit abnormal spermiogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
