Primary Identifier | MGI:1914272 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 229211 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable long-chain fatty acyl-CoA dehydrogenase activity and medium-chain fatty acyl-CoA dehydrogenase activity. Predicted to be involved in long-chain fatty acid metabolic process; medium-chain fatty acid metabolic process; and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study nuclear type mitochondrial complex I deficiency 20. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 20. Orthologous to human ACAD9 (acyl-CoA dehydrogenase family member 9). PHENOTYPE: Mice homozygous for a null allele exhibit perinatal lethality. Conditional deletion in cardiac or muscle tissue leads to various phenotypes observed in nuclear type mitochondrial complex I deficiency 20. [provided by MGI curators] |