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Protein Coding Gene : Qrfpr pyroglutamylated RFamide peptide receptor

Primary Identifier  MGI:2677633 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  229214
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cellular response to hormone stimulus. Located in non-motile cilium. Is expressed in ventral pallium. Used to study bone structure disease. Orthologous to human QRFPR (pyroglutamylated RFamide peptide receptor).
PHENOTYPE: Mice homozygous for a mutation diisplay kyphosis with abnormal vertebrae morphology and development including osteopenia of the vertebrae. Knock-out mice do not show a metabolic phenotype but show no increase in food intake or activity in response to the RFamide QRFP. [provided by MGI curators]
  • synonyms:
  • Gpr103a,
  • AQ27,
  • Qrfpr,
  • Gpr103,
  • G protein-coupled receptor 103,
  • pyroglutamylated RFamide peptide receptor

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Canonical gene --> Transcripts in specific strains.

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