Primary Identifier | MGI:2677633 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 229214 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cellular response to hormone stimulus. Located in non-motile cilium. Is expressed in ventral pallium. Used to study bone structure disease. Orthologous to human QRFPR (pyroglutamylated RFamide peptide receptor). PHENOTYPE: Mice homozygous for a mutation diisplay kyphosis with abnormal vertebrae morphology and development including osteopenia of the vertebrae. Knock-out mice do not show a metabolic phenotype but show no increase in food intake or activity in response to the RFamide QRFP. [provided by MGI curators] |