Primary Identifier | MGI:1920583 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 73333 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP:ADP antiporter activity. Involved in male meiosis I; regulation of mitochondrial membrane permeability; and spermatogenesis. Located in mitochondrial inner membrane. Part of mitochondrial permeability transition pore complex. Is expressed in genitourinary system; lung; pituitary gland; and vertebral axis musculature. Orthologous to human SLC25A31 (solute carrier family 25 member 31). PHENOTYPE: Male mice homozygous for a null allele exhibit infertility, arrested meiosis and increased apoptosis of the spermatocytes. [provided by MGI curators] |