| Primary Identifier | MGI:1926321 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 50706 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables heparin binding activity. Involved in cell adhesion and cellular response to vitamin K. Acts upstream of or within extracellular matrix organization; regulation of Notch signaling pathway; and tissue development. Located in collagen-containing extracellular matrix. Is expressed in several structures, including embryo mesenchyme; extraembryonic component; genitourinary system; heart and pericardium; and nervous system. Used to study aggressive periodontitis and bone structure disease. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human POSTN (periostin). PHENOTYPE: Homozygous null mice display abnormalities of the enamel, periodontal ligament, ameloblasts, and incisors. For one allele changing the hardness of the food alters the severity of the abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
