| Primary Identifier | MGI:2139806 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 229285 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable lipid binding activity and ubiquitin protein ligase binding activity. Involved in lipophagy. Acts upstream of or within several processes, including adipose tissue development; negative regulation of BMP signaling pathway; and negative regulation of collateral sprouting in absence of injury. Located in lipid droplet and synapse. Is expressed in dorsal root ganglion; olfactory epithelium; and trigeminal ganglion. Used to study Troyer syndrome. Human ortholog(s) of this gene implicated in Troyer syndrome. Orthologous to human SPART (spartin). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired lipid droplet amintenance, cytokinesis and impaired motor coordination. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
