Primary Identifier | MGI:2159210 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 99929 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables NAD+-protein poly-ADP-ribosyltransferase activity. Acts upstream of or within several processes, including face morphogenesis; steroid metabolic process; and vasculogenesis. Predicted to be active in nucleus. Is expressed in bladder; reproductive system; telencephalon; and tongue. Orthologous to human TIPARP (TCDD inducible poly(ADP-ribose) polymerase). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit postnatal lethality, skeletal and craniofacial defects, kidney defects and embryonic hemorrhaging. [provided by MGI curators] |