| Primary Identifier | MGI:2679447 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 386750 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in regulation of presynapse assembly. Acts upstream of or within several processes, including GABAergic synaptic transmission; positive regulation of synapse assembly; and synapse organization. Located in cell surface. Is active in GABA-ergic synapse and postsynaptic membrane. Is expressed in alimentary system; bladder; central nervous system; neural retina; and peripheral nervous system. Orthologous to human SLITRK3 (SLIT and NTRK like family member 3). PHENOTYPE: Mice homozygous for a knock-out mice exhibit reduced inhibitory synapse density, decreased miniature inhibitory postsynaptic current frequency and increased susceptibility to spontaneous and pharmacologically-induced seizures. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
