Primary Identifier | MGI:1858197 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 53317 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within positive regulation of G1/S transition of mitotic cell cycle and protein localization to nucleus. Predicted to be located in fibrillar center; nuclear membrane; and nuclear speck. Predicted to be part of DNA replication factor A complex; Prp19 complex; and U2-type catalytic step 2 spliceosome. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human PLRG1 (pleiotropic regulator 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality by E1.5. [provided by MGI curators] |