| Primary Identifier | MGI:1346022 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 23937 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within camera-type eye development; embryonic body morphogenesis; and positive regulation of cell population proliferation. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; limb; and sensory organ. Human ortholog(s) of this gene implicated in coloboma and syndromic microphthalmia 14. Orthologous to human MAB21L2 (mab-21 like 2). PHENOTYPE: Homozygous mutation of this gene results in omphalocele and defects in ventral body wall formation resulting in death at mid-gestation. Mutants have impaired development of the retina and lens. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
