Primary Identifier | MGI:1933397 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 80891 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein phosphatase binding activity; signaling adaptor activity; and transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway and immune response. Predicted to be located in cell surface. Predicted to be active in external side of plasma membrane. Orthologous to human FCRL2 (Fc receptor like 2). PHENOTYPE: Female homozygous mutant mice are larger than controls and show increased mean body weight, total tissue mass, lean body mass and total body fat. Homozygous mutant mice eshow a decreased mean percentage of CD8 cells in the peripheral blood. [provided by MGI curators] |