| Primary Identifier | MGI:1346037 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 23920 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable insulin receptor activity and insulin receptor substrate binding activity. Involved in cellular response to alkaline pH and protein autophosphorylation. Acts upstream of or within male sex determination. Predicted to be located in membrane. Predicted to be part of insulin receptor complex. Predicted to be active in axon and plasma membrane. Is expressed in brain; early conceptus; ganglia; metanephros; and pancreas. Orthologous to human INSRR (insulin receptor related receptor). PHENOTYPE: Mice homozygous for a targeted null mutation exhibit no anomalies in pancreatic islet morphology, beta-cell mass or pancreatic secretory function. This mutation in combination with Insr mutant mice does not affect the diabetes predisposition of Insr mutant mice. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
