| Primary Identifier | MGI:1351596 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 27371 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein-macromolecule adaptor activity. Acts upstream of or within T cell proliferation. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in juvenile rheumatoid arthritis and multiple sclerosis. Orthologous to human SH2D2A (SH2 domain containing 2A). PHENOTYPE: While T cell development is normal, T cell proliferation in response to TCR-mediated activation is impaired in homozygous null mice. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
