Primary Identifier | MGI:88491 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 12904 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables retinoic acid binding activity. Acts upstream of or within embryonic forelimb morphogenesis; positive regulation of collateral sprouting; and retinoic acid metabolic process. Located in endoplasmic reticulum and nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; heart and pericardium; and sensory organ. Orthologous to human CRABP2 (cellular retinoic acid binding protein 2). PHENOTYPE: Homozygotes for targeted null mutations may exhibit an additional postaxial digit, usually on a single forepaw. Penetrance is dependent on the genetic background. [provided by MGI curators] |