Primary Identifier | MGI:1096385 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 12032 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity; carbohydrate binding activity; and hyaluronic acid binding activity. Involved in synapse maturation. Acts upstream of or within hippocampus development. Located in perineuronal net. Is active in glutamatergic synapse. Is expressed in several structures, including brain; genitourinary system; lower jaw; sensory organ; and spinal cord. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human BCAN (brevican). PHENOTYPE: Homozygous mutation of this gene results in impaired LTP maintenance, but mutant animals show normal behavior and spatial learning capabilities. [provided by MGI curators] |