| Primary Identifier | MGI:2447364 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 229512 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable enzyme binding activity; telomerase RNA binding activity; and telomeric repeat DNA binding activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; regulation of dephosphorylation; and regulation of telomere maintenance. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleus. Predicted to be part of telomerase holoenzyme complex. Is expressed in mandible. Orthologous to human SMG5 (SMG5 nonsense mediated mRNA decay factor). PHENOTYPE: Homozygous knock-out embryos die before E13.5. [provided by MGI curators] |