| Primary Identifier | MGI:103236 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 13636 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ephrin receptor binding activity. Involved in several processes, including ephrin receptor signaling pathway; heart valve morphogenesis; and negative regulation of dendritic spine morphogenesis. Acts upstream of or within several processes, including negative regulation of thymocyte apoptotic process; nervous system development; and regulation of MAPK cascade. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Orthologous to human EFNA1 (ephrin A1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased cardiac muscle contractility associated with increased mitral and aortic valve thickness and increased epithelial to mesenchyme transition in outflow tract endocardial cushions. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
