| Primary Identifier | MGI:1916161 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 68911 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity; histone acetyltransferase regulator activity; and histone binding activity. Involved in canonical Wnt signaling pathway. Acts upstream of or within several processes, including lens development in camera-type eye; regulation of mammary gland epithelial cell proliferation; and spermatid nucleus differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and skin. Orthologous to human PYGO2 (pygopus family PHD finger 2). PHENOTYPE: Mice homozygous for a null allele exhibit neonatal lethality, have small or absent lens, abnormal optic cup morphology, and impaired mammary gland epithelium proliferation. Mice homozygous for a knock-in allele exhibit normal development and fertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
