| Primary Identifier | MGI:97475 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 18484 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables peptidylamidoglycolate lyase activity and peptidylglycine monooxygenase activity. Involved in peptide amidation and protein maturation. Predicted to be located in several cellular components, including perikaryon; secretory granule membrane; and trans-Golgi network. Predicted to be active in extracellular region. Is expressed in several structures, including alimentary system; central nervous system; forelimb bud; limb interdigital region; and sensory organ. Orthologous to human PAM (peptidylglycine alpha-amidating monooxygenase). PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality during fetal growth and development, edema, abnormal yolk sac vasculature, thin arterial walls, and abnormal bronchial epithelial morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
