| Primary Identifier | MGI:88244 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 20201 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Acts upstream of or within astrocyte development and positive regulation of peptide secretion. Predicted to be located in cytosol; extracellular space; and intermediate filament cytoskeleton. Predicted to be part of calprotectin complex. Predicted to be active in cytoplasm. Is expressed in several structures, including bone marrow; extraembryonic component; liver; mesometrium; and placenta. Human ortholog(s) of this gene implicated in myocarditis. Orthologous to human S100A8 (S100 calcium binding protein A8). PHENOTYPE: Homozygous disruption of this gene results in complete embryonic lethality. The exact timing of lethality varies between alleles. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
