Primary Identifier | MGI:1338947 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 20202 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Involved in peptidyl-cysteine S-nitrosylation; positive regulation of blood coagulation; and regulation of translation. Acts upstream of or within several processes, including astrocyte development; leukocyte chemotaxis; and regulation of integrin biosynthetic process. Is active in cornified envelope. Is expressed in several structures, including jaw; liver; otic capsule; skeleton; and spleen red pulp. Human ortholog(s) of this gene implicated in myocarditis. Orthologous to human S100A9 (S100 calcium binding protein A9). PHENOTYPE: Mice homozygous for one null allele exhibit abnormal immune physiology. [provided by MGI curators] |