Primary Identifier | MGI:96945 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 17235 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in flagellated sperm motility. Acts upstream of or within binding activity of sperm to zona pellucida and penetration of zona pellucida. Located in mitochondrion. Is expressed in testis. Orthologous to human SMCP (sperm mitochondria associated cysteine rich protein). PHENOTYPE: On a 129 inbred background, males homozygous for a targeted null mutation produce sperm with reduced motility and capacity to penetrate oocytes resulting in infertility. Noninbred mutant males are normally fertile. [provided by MGI curators] |