Primary Identifier | MGI:1858170 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 53814 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ornithine decarboxylase inhibitor activity. Involved in negative regulation of polyamine transmembrane transport; positive regulation of intracellular protein transport; and positive regulation of protein catabolic process. Located in cytoplasm and nucleus. Orthologous to human OAZ3 (ornithine decarboxylase antizyme 3). PHENOTYPE: Homozygotes for a targeted null mutation exhibit male infertility due to detachment of sperm tail and head during sperm maturation. [provided by MGI curators] |