| Primary Identifier | MGI:2445001 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 226407 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable GTPase activator activity; guanyl-nucleotide exchange factor activity; and small GTPase binding activity. Involved in several processes, including Rab protein signal transduction; excitatory postsynaptic potential; and modulation of chemical synaptic transmission. Predicted to be located in cis-Golgi network; endoplasmic reticulum tubular network; and excitatory synapse. Predicted to be part of protein-containing complex. Is expressed in brain and neural retina. Human ortholog(s) of this gene implicated in Warburg micro syndrome 1. Orthologous to human RAB3GAP1 (RAB3 GTPase activating protein catalytic subunit 1). PHENOTYPE: Mice homozygous for a null mutation display abnormal synaptic transmission but have normal gross brain morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
