Primary Identifier | MGI:2448415 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 319190 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable lipopolysaccharide binding activity. Predicted to be involved in defense response to other organism; killing of cells of another organism; and negative regulation of tumor necrosis factor-mediated signaling pathway. Predicted to be located in cytosol; extracellular space; and nucleoplasm. Predicted to be part of CENP-A containing nucleosome. Predicted to colocalize with plasma membrane. Is expressed in cerebral cortex ventricular layer; olfactory epithelium; and vomeronasal organ. Orthologous to human H2BC11 (H2B clustered histone 11). PHENOTYPE: Mice homozygous for a null allele exhibit impaired olfactory function and an increased lifespan of mature olfactory sensory neurons associated with decreased neuron apoptosis. [provided by MGI curators] |