| Primary Identifier | MGI:1860383 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 54215 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables MHC class I protein complex binding activity. Involved in mucosal immune response; positive regulation of natural killer cell mediated immune response to tumor cell; and positive regulation of type II interferon production. Acts upstream of or within defense response to Gram-negative bacterium. Located in plasma membrane. Orthologous to human CD160 (CD160 molecule). PHENOTYPE: Mice homozygous for a knock-out allele show decreased interferon-gamma secretion by NK cells and increased tumor growth/size following inoculation with NK-dependent B16 tumor cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
