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Protein Coding Gene : Wars2 tryptophanyl tRNA synthetase 2 (mitochondrial)
Primary Identifier  MGI:1917810 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  70560
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable tryptophan-tRNA ligase activity. Acts upstream of or within vasculogenesis. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; ear; genitourinary system; and skeleton. Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
PHENOTYPE: Mice homozygous for an ENU-induced mutation exhibit decreased body fat mass, cardiomyopathy, and progressive hearing loss. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 5730427B17 gene,
  • tryptophanyl tRNA synthetase 2 (mitochondrial),
  • MGI:2139688,
  • MGI:1924510,
  • 9430020O07Rik,
  • TrpRS,
  • expressed sequence AI413375,
  • Wars2,
  • AI413375,
  • 5730427B17Rik,
  • RIKEN cDNA 9430020O07 gene
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2 Involved In Mutations

Trail: ProteinCodingGene

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