Primary Identifier | MGI:2443143 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 269470 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in nuclear membrane; nucleolus; and nucleoplasm. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Is expressed in cerebral cortex ventricular layer. Human ortholog(s) of this gene implicated in papillary thyroid carcinoma. Orthologous to human WDR3 (WD repeat domain 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete prenatal lethality. Heterozygotes show normal growth and brain anatomy but exhibit a slight but significant increase in spontaneous locomotor activity. [provided by MGI curators] |